C19ORF80 Antikörper (N-Term)

Produktnummer ABIN6991947

Der Kaninchen Polyklonal anti-C19ORF80 Antikörper (ABIN6991947) detektiert spezifisch C19ORF80 in WB, ELISA, IHC (p) und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für C19ORF80 Antikörper (N-Term) (ABIN6991947)

Target: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C19ORF80 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-C19ORF80 Antikörper

Bindungsspezifität: AA 40-90, N-Term

Spezifität: Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist, this antibody will detect the two largest isoforms.

Aufreinigung: Betatrophin antibody is affinity chromatography purified via peptide column.

Immunogen: Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin. The immunogen is located within amino acids 40 - 90 of Betatrophin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Betatrophin antibody can be used for detection of Betatrophin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Betatrophin antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Betatrophin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu C19ORF80

Target: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Andere Bezeichnung: Betatrophin

Hintergrund: The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).

Molekulargewicht: Predicted: 22 kDa

Observed: 22 kDa

Gen-ID: 55908

NCBI Accession: NP_061157

UniProt: Q6UXH0