Dynamin 1-Like Antikörper (AA 530-580)

Produktnummer ABIN6991941

Dieses Anti-Dynamin 1-Like-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Dynamin 1-Like in WB, ELISA, IF und ICC. Geeignet für Human und Maus.

Kurzübersicht für Dynamin 1-Like Antikörper (AA 530-580) (ABIN6991941)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Dynamin 1-Like Antikörper

Bindungsspezifität: AA 530-580

Spezifität: DNM1L antibody is human and mouse reactive. At least four isoforms of DNM1L are known to exist, this antibody will detect the two longest isoforms.

Aufreinigung: DNM1L antibody is affinity chromatography purified via peptide column.

Immunogen: DNM1L antibody was raised against a 19 amino acid peptide near the center of human DNM1L. The immunogen is located within amino acids 530 - 580 of DNM1L.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DNM1L antibody can be used for detection of DNM1L by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DNM1L antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DNM1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DNM1L

Hintergrund: The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1). DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2). Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3).

Molekulargewicht: Predicted: 81 kDa

Observed: 80 kDa

Gen-ID: 10059

NCBI Accession: NP_036192

UniProt: O00429