IL-22 Antikörper (AA 90-140)

Produktnummer ABIN6991937

Produktdetails anti-IL-22 Antikörper

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Bindungsspezifität: AA 90-140

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: IL-22 antibody is human, mouse, and rat reactive. Multiple isoforms of IL-22 are known to exist.

Aufreinigung: IL-22 antibody is affinity chromatography purified via peptide column.

Immunogen: IL-22 antibody was raised against a 17 amino acid peptide near the center of human IL-22 . The immunogen is located within amino acids 90 - 140 of IL-22.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-22 antibody can be used for detection of IL-22 by Western blot at 0.5 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-22 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-22 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IL-22

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Andere Bezeichnung: IL-22 (IL22 Produkte)

Synonyme: IL-21 antikoerper, IL-22 antikoerper, IL-D110 antikoerper, IL-TIF antikoerper, ILTIF antikoerper, TIFIL-23 antikoerper, TIFa antikoerper, zcyto18 antikoerper, IL-22a antikoerper, ILTIFa antikoerper, Iltif antikoerper, RGD1561292 antikoerper, interleukin-22 antikoerper, interleukin 22 antikoerper, IL22 antikoerper, il22 antikoerper, Il22 antikoerper

Hintergrund: Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3).

Molekulargewicht: Predicted: 20 kDa

Observed: 17 kDa

Gen-ID: 50616

NCBI Accession: NP_065386

UniProt: Q9GZX6