Der Kaninchen Polyklonal Anti-BHLHA15-Antikörper wurde für ELISA, WB, IF und IHC (p) validiert. Er ist geeignet, BHLHA15 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN6991922
Kurzübersicht für BHLHA15 Antikörper (AA 60-110) (ABIN6991922)
BHLHA15 antibody is human, mouse and rat reactive.
Aufreinigung
BHLHA15 antibody is affinity chromatography purified via peptide column.
Immunogen
BHLHA15 antibody was raised against a 18 amino acid peptide near the center of human BHLHA15. The immunogen is located within amino acids 60 - 110 of BHLHA15.
BHLHA15 antibody can be used for detection of BHLHA15 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
BHLHA15 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
BHLHA15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
BHLHA15
(Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))
Andere Bezeichnung
BHLHA15
Hintergrund
BHLHA15 (basic helix-loop-helix protein 15), also known as MIST1 (muscle intestine and stomach expression 1) belongs to the bHLH family of transcription factors and plays a role in regulating the transcriptional activity of MYOD1 in muscle cell development as well as serving as a key regulator of acinar cell function (1,2). BHLHA15 contains a basic helix-loop-helix (bHLH) domain and is capable of binding to E-box motifs as a homodimer or a heterodimer with E-proteins. It may also negatively regulate bHLH-mediated transcription through a N-terminal repressor domain (3). It is expressed in mammary epithelial cells and is essential for the regulation of mammary gland development (4).