IL1F9 Antikörper (C-Term)
Kurzübersicht für IL1F9 Antikörper (C-Term) (ABIN6991917)
Target
Alle IL1F9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- IL-36G antibody is human specific. IL-36G antibody will not cross-react with IL-36A or IL-36B.
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Aufreinigung
- IL-36G antibody is affinity chromatography purified via peptide column.
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Immunogen
- IL-36G antibody was raised against a 13 amino acid peptide near the carboxy terminus of human IL-36G. The immunogen is located within the last 50 amino acids of IL-36G.
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Isotyp
- IgG
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Applikationshinweise
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IL-36G antibody can be used for detection of IL-36G by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- IL-36G antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- IL-36G antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
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Andere Bezeichnung
- IL-36G
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Hintergrund
- IL-36G is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36G is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36B, IL-36G requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). IL-36G expression is stimulated by interferon-gamma, tumor necrosis factor-alpha and interleukin 1 (4). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (5).
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Molekulargewicht
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Predicted: 19 kDa
Observed: 22 kDa -
Gen-ID
- 56300
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NCBI Accession
- NP_062564
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UniProt
- Q9NZH8
Target
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