IL-1F10 antibody is human, mouse and rat reactive. Two isoforms of IL-1F10 exist.
Aufreinigung
IL-1F10 antibody is affinity chromatography purified via peptide column.
Immunogen
Anti-IL-1F10 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human IL-1F10. The immunogen is located within the last 50 amino acids of IL-1F10.
IL1F10
Reaktivität: Human
Wirt: Maus
Monoclonal
Biotin
Applikationshinweise
WB: 1 μ,g/mL, IHC: 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
IL-1F10 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
IL-1F10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
IL1F10
(Interleukin 1 Family, Member 10 (Theta) (IL1F10))
Andere Bezeichnung
IL-1F10
Hintergrund
The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection (1). IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil (2). IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses (3). IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis (4).