SOGA1 Antikörper (C-Term)

Produktnummer ABIN6991908

Dieses Anti-SOGA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SOGA1 in WB, ELISA und IF. Geeignet für Human.

Kurzübersicht für SOGA1 Antikörper (C-Term) (ABIN6991908)

Target: SOGA1 (Suppressor of Glucose, Autophagy Associated 1 (SOGA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-SOGA1 Antikörper

Bindungsspezifität: C-Term

Spezifität: SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.

Aufreinigung: SOGA1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SOGA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SOGA1

Target: SOGA1 (Suppressor of Glucose, Autophagy Associated 1 (SOGA1))

Andere Bezeichnung: SOGA1

Hintergrund: The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).

Molekulargewicht: Predicted: 183 kDa

Observed: 200kDa

Gen-ID: 140710

NCBI Accession: NP_954650

UniProt: O94964