PHF14 Antikörper (N-Term)

Produktnummer ABIN6991907

Der Kaninchen Polyklonal Anti-PHF14-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, PHF14 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PHF14 Antikörper (N-Term) (ABIN6991907)

Target: PHF14 (PHD Finger Protein 14 (PHF14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-PHF14 Antikörper

Bindungsspezifität: AA 210-260, N-Term

Spezifität: PHF14 antibody is human, mouse and rat reactive. Multiple isoforms of PHF14 are known to exist.

Aufreinigung: PHF14 Antibody is affinity chromatography purified via peptide column.

Immunogen: PHF14 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHF14. The immunogen is located within amino acids 210 - 260 of PHF14 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PHF14 antibody can be used for detection of PHF14 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PHF14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PHF14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PHF14

Target: PHF14 (PHD Finger Protein 14 (PHF14))

Andere Bezeichnung: PHF14

Hintergrund: PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development (1). PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2), and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3).

Molekulargewicht: Predicted: 98 kDa

Observed: 100kDa

Gen-ID: 9678

NCBI Accession: NP_055475

UniProt: O94880