TMEM107 Antikörper (N-Term)

Produktnummer ABIN6991906

Produktdetails anti-TMEM107 Antikörper

Target: TMEM107 (Transmembrane Protein 107 (TMEM107))

Bindungsspezifität: AA 20-70, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM107 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (IF)

Spezifität: TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.

Aufreinigung: TMEM107 Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107. The immunogen is located within amino acids 20 - 70 of TMEM107 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TMEM107 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TMEM107antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TMEM107

Target: TMEM107 (Transmembrane Protein 107 (TMEM107))

Andere Bezeichnung: TMEM107 (TMEM107 Produkte)

Synonyme: zgc:77926 antikoerper, MGC157051 antikoerper, GRVS638 antikoerper, PRO1268 antikoerper, 1110004B13Rik antikoerper, 2810049P21Rik antikoerper, transmembrane protein 107 antikoerper, Transmembrane protein 107 antikoerper, transmembrane protein 107 L homeolog antikoerper, tmem107 antikoerper, TMEM107 antikoerper, Tmem107 antikoerper, Tsp_08866 antikoerper, tm107 antikoerper, tmem107.L antikoerper

Hintergrund: Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).

Molekulargewicht: Predicted: 16 kDa

Observed: 19kDa

Gen-ID: 84314

NCBI Accession: NP_115730

UniProt: Q6UX40