T-Bet Antikörper (C-Term)

Produktnummer ABIN6991904

Produktdetails anti-T-Bet Antikörper

Target: T-Bet

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Bet Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: TBX21 antibody is human and mouse reactive.

Aufreinigung: TBX21 Antibody is affinity chromatography purified via peptide column.

Immunogen: TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2. The immunogen is located within the last 50 amino acids of TBX21 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TBX21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TBX21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu T-Bet

Target: T-Bet

Andere Bezeichnung: TBX21 (T-Bet Produkte)

Synonyme: T-PET antikoerper, T-bet antikoerper, TBET antikoerper, TBLYM antikoerper, TBT1 antikoerper, Tbet antikoerper, Tblym antikoerper, T-box 21 antikoerper, TBX21 antikoerper, Tbx21 antikoerper

Hintergrund: TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1,2). Members of this family include transcription factors involved in the regulation of developmental processes (2). Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1,3). Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3).

Molekulargewicht: Predicted: 59 kDa

Observed: 55kDa

Gen-ID: 30009

NCBI Accession: NP_037483

UniProt: Q9UL17