T-Bet Antikörper (C-Term)
Kurzübersicht für T-Bet Antikörper (C-Term) (ABIN6991904)
Target
Alle T-Bet Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- TBX21 antibody is human and mouse reactive.
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Aufreinigung
- TBX21 Antibody is affinity chromatography purified via peptide column.
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Immunogen
- TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2. The immunogen is located within the last 50 amino acids of TBX21 .
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Isotyp
- IgG
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Applikationshinweise
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TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- TBX21 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- TBX21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- T-Bet
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Andere Bezeichnung
- TBX21
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Hintergrund
- TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1,2). Members of this family include transcription factors involved in the regulation of developmental processes (2). Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1,3). Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3).
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Molekulargewicht
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Predicted: 59 kDa
Observed: 55kDa -
Gen-ID
- 30009
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NCBI Accession
- NP_037483
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UniProt
- Q9UL17
Target
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