CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.
Aufreinigung
CD160 Antibody is affinity chromatography purified via peptide column.
Immunogen
CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160. The immunogen is located within amino acids 50 - 100 of CD160 .
CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
CD160 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
CD160 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
CD160
Andere Bezeichnung
CD160
Hintergrund
CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).