ERAP2 Antikörper (N-Term)

Produktnummer ABIN6991900

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ERAP2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ERAP2 Antikörper (N-Term) (ABIN6991900)

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ERAP2 Antikörper

Bindungsspezifität: AA 110-160, N-Term

Spezifität: ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.

Aufreinigung: ERAP2 Antibody is affinity chromatography purified via peptide column.

Immunogen: ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ERAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu ERAP2

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Andere Bezeichnung: ERAP2

Hintergrund: The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).

Molekulargewicht: Predicted: 106 kDa

Observed: 120kDa

Gen-ID: 64167

NCBI Accession: NP_071745

UniProt: Q6P179