DDC Antikörper (C-Term)

Produktnummer ABIN6991892

Der Kaninchen Polyklonal Anti-DDC-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, DDC in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für DDC Antikörper (C-Term) (ABIN6991892)

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DDC Antikörper

Bindungsspezifität: AA 390-440, C-Term

Spezifität: DDC antibody is human, mouse and rat reactive.

Aufreinigung: DDC Antibody is affinity chromatography purified via peptide column.

Immunogen: DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DDC Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DDC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Andere Bezeichnung: DDC

Hintergrund: DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).

Molekulargewicht: Predicted: 53 kDa

Observed: 53 kDa

Gen-ID: 1644

NCBI Accession: NP_000781

UniProt: P20711

Pathways: Dopaminergic Neurogenesis