KHDC1 Antikörper (N-Term)

Produktnummer ABIN6991883

Der Kaninchen Polyklonal Anti-KHDC1-Antikörper wurde für ELISA, WB und IHC (p) validiert. Er ist geeignet, KHDC1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für KHDC1 Antikörper (N-Term) (ABIN6991883)

Target: KHDC1 (KH Homology Domain Containing 1 (KHDC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KHDC1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KHDC1 Antikörper

Bindungsspezifität: AA 30-80, N-Term

Spezifität: KHDC1 antibody is human, mouse and rat reactive. At least three isoforms of KHDC1 are known to exist, this antibody will only detect the longest isoform.

Aufreinigung: KHDC1 Antibody is affinity chromatography purified via peptide column.

Immunogen: KHDC1 antibody was raised against a 15 amino acid peptide near the amino terminus of human KHDC1. The immunogen is located within amino acids 30 - 80 of KHDC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KHDC1 antibody can be used for detection of KHDC1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KHDC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KHDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu KHDC1

Target: KHDC1 (KH Homology Domain Containing 1 (KHDC1))

Andere Bezeichnung: KHDC1

Hintergrund: KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).

Molekulargewicht: Predicted: 18 kDa

Observed: 26 kDa

Gen-ID: 80759

NCBI Accession: NP_085045

UniProt: Q4VXA5