Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BimEL in WB, ELISA, ICC und IF. Er zeigt eine Reaktivität gegenüber Ratte, Human und Maus.
Produktnummer ABIN6991882
Kurzübersicht für BimEL Antikörper (N-Term) (ABIN6991882)
Target
BimEL
Reaktivität
Ratte, Human, Maus
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Dieser BimEL Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
Bindungsspezifität
AA 20-70, N-Term
Spezifität
Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.
Aufreinigung
Bim EL Antibody is affinity chromatography purified via peptide column.
Immunogen
Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim. The immunogen is located within amino acids 20 - 70 of Bim EL.
Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
BimEL
Andere Bezeichnung
Bim EL
Hintergrund
Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).