TLX3 Antikörper (N-Term)

Produktnummer ABIN6991868

Der Kaninchen Polyklonal Anti-TLX3-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, TLX3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TLX3 Antikörper (N-Term) (ABIN6991868)

Target: TLX3 (T-Cell Leukemia Homeobox 3 (TLX3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-TLX3 Antikörper

Bindungsspezifität: N-Term

Spezifität: TLX3 antibody is predicted to not cross-react with other TLX proteins.

Aufreinigung: TLX3 Antibody is affinity chromatography purified via peptide column.

Immunogen: TLX3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX3. The immunogen is located within the first 50 amino acids of TLX3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TLX3 antibody can be used for detection of TLX3 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TLX3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TLX3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TLX3

Target: TLX3 (T-Cell Leukemia Homeobox 3 (TLX3))

Andere Bezeichnung: TLX3

Hintergrund: TLX3 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).

Molekulargewicht: Predicted: 32 kDa

Observed: 30 kDa

Gen-ID: 30012

NCBI Accession: NP_066305

UniProt: O43711