TLX1 Antikörper (N-Term)

Produktnummer ABIN6991866

Dieses Anti-TLX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLX1 in WB, ELISA und IHC (p). Geeignet für Maus, Human und Ratte.

Kurzübersicht für TLX1 Antikörper (N-Term) (ABIN6991866)

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TLX1 Antikörper

Bindungsspezifität: N-Term

Spezifität: Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.

Aufreinigung: TLX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: TLX1 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX1. The immunogen is located within the first 50 amino acids of TLX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TLX1 antibody can be used for detection of TLX1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TLX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TLX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TLX1

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Andere Bezeichnung: TLX1

Hintergrund: TLX1 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.

Molekulargewicht: Predicted: 36 kDa

Observed: 35 kDa

Gen-ID: 3195

NCBI Accession: NP_005512

UniProt: P31314