DDX41 Antikörper (N-Term)

Produktnummer ABIN6991862

Der Kaninchen Polyklonal Anti-DDX41-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, DDX41 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für DDX41 Antikörper (N-Term) (ABIN6991862)

Target: DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DDX41 Antikörper

Bindungsspezifität: AA 230-280, N-Term

Spezifität: At least two isoforms of DDX41 are known to exist, this antibody will detect both isoforms.

Aufreinigung: DDX41 Antibody is affinity chromatography purified via peptide column.

Immunogen: DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41. The immunogen is located within amino acids 230 - 280 of DDX41.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DDX41 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DDX41 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu DDX41

Target: DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))

Andere Bezeichnung: DDX41

Hintergrund: DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.

Molekulargewicht: Predicted: 68 kDa

Observed: 70 kDa

Gen-ID: 51428

NCBI Accession: NP_057306

UniProt: Q9UJV9