PRRT2 Antikörper (AA 180-230)

Produktnummer ABIN6991846

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PRRT2 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PRRT2 Antikörper (AA 180-230) (ABIN6991846)

Target: PRRT2 (Proline-Rich Transmembrane Protein 2 (PRRT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRRT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PRRT2 Antikörper

Bindungsspezifität: AA 180-230

Spezifität: Multiple isoforms of PRRT2 are known to exist.

Aufreinigung: PRRT2 Antibody is affinity chromatography purified via peptide column.

Immunogen: PRRT2 antibody was raised against a 18 amino acid peptide near the center of human PRRT2 . The immunogen is located within amino acids 180 - 230 of PRRT2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PRRT2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PRRT2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PRRT2

Target: PRRT2 (Proline-Rich Transmembrane Protein 2 (PRRT2))

Andere Bezeichnung: PRRT2

Hintergrund: PRRT2 Antibody: The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.

Molekulargewicht: Predicted: 43 kDa

Observed: 44 kDa

Gen-ID: 112476

NCBI Accession: NP_001243371

UniProt: Q7Z6L0