C1orf64 Antikörper (C-Term)

Produktnummer ABIN6991843

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch C1orf64 in ELISA, WB, IHC (p) und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für C1orf64 Antikörper (C-Term) (ABIN6991843)

Target: C1orf64 (C1ORF64) (Chromosome 1 Open Reading Frame 64 (C1ORF64))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1orf64 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-C1orf64 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: ERRF Antibody is affinity chromatography purified via peptide column.

Immunogen: ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF . The immunogen is located within the last 50 amino acids of ERRF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ERRF Antibody can be used for detection of ERRF by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ERRF Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ERRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu C1orf64

Target: C1orf64 (C1ORF64) (Chromosome 1 Open Reading Frame 64 (C1ORF64))

Andere Bezeichnung: ERRF

Hintergrund: ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

Molekulargewicht: Predicted: 19 kDa

Observed: 15 kDa

Gen-ID: 149563

NCBI Accession: NP_849162

UniProt: Q8NEQ6