Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MTERFD1 in WB, ELISA, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human und Maus.
At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.
Aufreinigung
MTERFD1 Antibody is affinity chromatography purified via peptide column.
Immunogen
MTERFD1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MTERFD1 . The immunogen is located within the last 50 amino acids of MTERFD1.
MTERFD1 Antibody can be used for detection of MTERFD1 by Western blot starting at 1 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
MTERFD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
MTERFD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
MTERFD1
(MTERF Domain Containing 1 (MTERFD1))
Andere Bezeichnung
MTERFD1
Hintergrund
MTERFD1 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD1 is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It binds promoter DNA and acts as a mitochondrial transcription regulator. It has been suggested that only the phosphorylated form of MTERFD1 has transcription termination activity. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.