SDPR Antikörper (N-Term)

Produktnummer ABIN6991833

Dieses Anti-SDPR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SDPR in WB, ELISA, IHC (p) und IF. Geeignet für Human.

Kurzübersicht für SDPR Antikörper (N-Term) (ABIN6991833)

Target: SDPR (Serum Deprivation Response (SDPR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SDPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-SDPR Antikörper

Bindungsspezifität: N-Term

Spezifität: It is predicted to not cross-react with other members of the cavin family.

Aufreinigung: SDPR Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR. The immunogen is located within the first 50 amino acids of SDPR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SDPR Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SDPR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SDPR

Target: SDPR (Serum Deprivation Response (SDPR))

Andere Bezeichnung: SDPR

Hintergrund: SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.

Molekulargewicht: Predicted: 22, 33, 43 kDa kDa

Observed: 30 kDa

Gen-ID: 8436

NCBI Accession: NP_004648

UniProt: O95810