RRAS2 Antikörper (C-Term)

Produktnummer ABIN6991827

Produktdetails anti-RRAS2 Antikörper

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Two isoforms of RRAS2 exists as a result of alternative splicing event.

Aufreinigung: RRAS2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal RRAS2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human RRAS2. The immunogen is located within the last 50 amino acids of RRAS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RRAS2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RRAS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu RRAS2

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Andere Bezeichnung: RRAS2 (RRAS2 Produkte)

Hintergrund: RRAS2 Antibody: Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60 % . RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.

Molekulargewicht: 22 kDa

Gen-ID: 22800

NCBI Accession: NP_036382

UniProt: P62070