GRIP1 Antikörper (C-Term)

Produktnummer ABIN6991819

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRIP1 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GRIP1 Antikörper (C-Term) (ABIN6991819)

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GRIP1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: GRIP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal GRIP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GRIP1. The immunogen is located within the last 50 amino acids of GRIP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GRIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GRIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GRIP1

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Andere Bezeichnung: GRIP1

Hintergrund: GRIP1 Antibody: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).

Molekulargewicht: Predicted: 118 kDa

Observed: 115 kDa

Gen-ID: 23426

NCBI Accession: NP_066973

UniProt: Q9Y3R0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway