CRB2 Antikörper (AA 460-510)
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- Target Alle CRB2 Antikörper anzeigen
- CRB2 (Crumbs Homolog 2 (CRB2))
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Bindungsspezifität
- AA 460-510
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CRB2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- At least three isoforms of CRB2 are known to exist, this antibody will detect all three. CRB2 antibody is predicted to not cross-react with other members of the CRB family.
- Aufreinigung
- CRB2 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- Rabbit polyclonal CRB2 antibody was raised against a 17 amino acid peptide near the center of human CRB2. The immunogen is located within amino acids 460 - 510 of CRB2.
- Isotyp
- IgG
- Top Product
- Discover our top product CRB2 Primärantikörper
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- Applikationshinweise
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CRB2 antibody can be used for detection of CRB2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- CRB2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- CRB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- CRB2 (Crumbs Homolog 2 (CRB2))
- Andere Bezeichnung
- CRB2 (CRB2 Produkte)
- Synonyme
- 5930402A21 antikoerper, BC043114 antikoerper, RGD1309368 antikoerper, crb2 antikoerper, crumbs family member 2 antikoerper, crumbs 2, cell polarity complex component antikoerper, crumbs family member 2a antikoerper, Crb2 antikoerper, CRB2 antikoerper, crb2a antikoerper
- Hintergrund
- CRB2 Antibody: CRB2 (Crumbs homolog 2), like its homologs CRB1 and CRB3, is similar to the Drosophila crumbs protein and is expressed in retina, brain and kidney. Along with other proteins, the Crumbs proteins form a complex that help set up cell polarity in developing neuroepithelial cells. At the onset of neural specification, embryonic stem cells (ESCs) upregulate CRB2, which then localizes apically in neural rosettes. Gain- and loss-of-function studies of CRB2 have shown that CRB2 is essential for the stabilization of other polarity proteins. Unlike CRB1, mutations in CRB2 do not appear to play a role in retinitis pigmentosa or in Leber congenital amaurosis.
- Molekulargewicht
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Predicted: 105, 129, and 141 kDa
Observed: 103, 128 kDa - Gen-ID
- 286204
- NCBI Accession
- NP_775960
- UniProt
- Q5IJ48
- Pathways
- Notch Signalweg
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