TSPY1L (C-Term) Antikörper
Reaktivität: Human, Maus
ELISA, WB
Wirt: Kaninchen
Polyclonal
unconjugated
-
- Target
- TSPY1L
- Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1L.
- Aufreinigung
- TSPY1L Antibody is affinity chromatography purified via peptide column.
- Immunogen
- Rabbit polyclonal TSPY1L antibody was raised against a 20 amino acid peptide near the carboxy terminus of human TSPY1L. The immunogen is located within the last 50 amino acids of TSPY1L.
- Isotyp
- IgG
-
- Applikationshinweise
-
TSPY1L antibody can be used for detection of TSPY1L by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- TSPY1L Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- TSPY1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- Target
- TSPY1L
- Hintergrund
- TSPY1L Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
- Molekulargewicht
- 34 kDa
- Gen-ID
- 7258
- NCBI Accession
- NP_003299
- UniProt
- Q01534
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