TSPY1L (C-Term) Antikörper

Produktnummer ABIN6991788

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in ELISA und WB. Geeignet für Human und Maus.

Kurzübersicht für TSPY1L (C-Term) Antikörper (ABIN6991788)

Target: TSPY1L

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: C-Term

Spezifität: TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1L.

Aufreinigung: TSPY1L Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal TSPY1L antibody was raised against a 20 amino acid peptide near the carboxy terminus of human TSPY1L. The immunogen is located within the last 50 amino acids of TSPY1L.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TSPY1L antibody can be used for detection of TSPY1L by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TSPY1L Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TSPY1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antigendetails

Target: TSPY1L

Hintergrund: TSPY1L Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Molekulargewicht: 34 kDa

Gen-ID: 7258

NCBI Accession: NP_003299

UniProt: Q01534