WIPI2 Antikörper (N-Term)

Produktnummer ABIN6991783

Produktdetails anti-WIPI2 Antikörper

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WIPI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: WIPI2 antibody is human and rat reactive. Multiple isoforms of WIPI2 are known to exist. WIPI2 antibody is predicted to not cross-react with WIPI1.

Aufreinigung: WIPI2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal WIPI2 antibody was raised against a 17 amino acid peptide near the amino terminus of human WIPI2. The immunogen is located within the first 50 amino acids of WIPI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WIPI2 antibody can be used for detection of WIPI2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: WIPI2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: WIPI2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu WIPI2

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Andere Bezeichnung: WIPI2 (WIPI2 Produkte)

Synonyme: ATG18B antikoerper, Atg21 antikoerper, WIPI-2 antikoerper, 1110018O08Rik antikoerper, 2510001I10Rik antikoerper, WD repeat domain, phosphoinositide interacting 2 L homeolog antikoerper, WD repeat domain, phosphoinositide interacting 2 antikoerper, wipi2.L antikoerper, WIPI2 antikoerper, Wipi2 antikoerper

Hintergrund: WIPI2 Antibody: WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.

Molekulargewicht: 50 kDa

Gen-ID: 26100

NCBI Accession: NP_056425

UniProt: Q9Y4P8