PANX1 Antikörper (N-Term)

Produktnummer ABIN6991780

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PANX1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für PANX1 Antikörper (N-Term) (ABIN6991780)

Target: PANX1 (Pannexin 1 (PANX1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PANX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-PANX1 Antikörper

Bindungsspezifität: AA 70-120, N-Term

Spezifität: Two transcript variants encoding different isoforms have been found for this gene.

Aufreinigung: PANX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1. The immunogen is located within amino acids 70 - 120 of PANX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PANX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PANX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PANX1

Target: PANX1 (Pannexin 1 (PANX1))

Andere Bezeichnung: PANX1

Hintergrund: PANX1 Antibody: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Molekulargewicht: 47 kDa

Gen-ID: 24145

NCBI Accession: NP_056183

UniProt: Q96RD7