ACSL1 Antikörper (AA 240-290)

Produktnummer ABIN6991772

Der Kaninchen Polyklonal Anti-ACSL1-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, ACSL1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ACSL1 Antikörper (AA 240-290) (ABIN6991772)

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-ACSL1 Antikörper

Bindungsspezifität: AA 240-290

Spezifität: At least three isoforms of ACSL1 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: ACSL1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal ACSL1 antibody was raised against an 18 amino acid peptide near the center of human ACSL1. The immunogen is located within amino acids 240 - 290 of ACSL1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ACSL1 antibody can be used for detection of ACSL1 by Western blot at 0.25 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ACSL1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ACSL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Andere Bezeichnung: ACSL1

Hintergrund: ACSL1 Antibody: Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ACSL1 is the major acyl-CoA enzyme in the heart, providing 60-90 % of heart ATP. Loss of ACSL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy.

Molekulargewicht: Predicted: 41, 58, 77 kDa

Observed: 45, 47 kDa 

Gen-ID: 2180

NCBI Accession: NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha