SGSM1 Antikörper (AA 480-530)

Produktnummer ABIN6991753

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SGSM1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SGSM1 Antikörper (AA 480-530) (ABIN6991753)

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-SGSM1 Antikörper

Bindungsspezifität: AA 480-530

Spezifität: At least four isoforms of SGSM1 are known to exist, SGSM1 antibody will detect all four isoforms.

Aufreinigung: SGSM1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1. The immunogen is located within amino acids 480 - 530 of SGSM1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SGSM1 antibody can be used for detection of SGSM1 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SGSM1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SGSM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SGSM1

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Andere Bezeichnung: SGSM1

Hintergrund: SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.

Molekulargewicht: 126 kDa

Gen-ID: 129049

NCBI Accession: NP_001035037

UniProt: Q2NKQ1