Myc Target 1 Antikörper (C-Term)
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- Target Alle Myc Target 1 (MYCT1) Antikörper anzeigen
- Myc Target 1 (MYCT1)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Myc Target 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.
- Aufreinigung
- MYCT1 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.
- Isotyp
- IgG
- Top Product
- Discover our top product MYCT1 Primärantikörper
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- Applikationshinweise
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MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- MYCT1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- Myc Target 1 (MYCT1)
- Andere Bezeichnung
- MYCT1 (MYCT1 Produkte)
- Synonyme
- MYCT1 antikoerper, MGC147166 antikoerper, si:dkey-12h9.2 antikoerper, MTLC antikoerper, 1110020B04Rik antikoerper, AI225941 antikoerper, AI642973 antikoerper, Mtmc1 antikoerper, myc target 1 antikoerper, MYC target 1 antikoerper, myc target 1a antikoerper, MYCT1 antikoerper, myct1 antikoerper, myct1a antikoerper, Myct1 antikoerper
- Hintergrund
- MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
- Molekulargewicht
- 26 kDa
- Gen-ID
- 80177
- NCBI Accession
- NP_079383
- UniProt
- Q8N699
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