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Myc Target 1 Antikörper (C-Term)

Dieses Anti-Myc Target 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Myc Target 1 in WB und ELISA. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN6991752

Kurzübersicht für Myc Target 1 Antikörper (C-Term) (ABIN6991752)

Target

Alle Myc Target 1 (MYCT1) Antikörper anzeigen
Myc Target 1 (MYCT1)

Reaktivität

  • 36
  • 19
  • 18
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 36
Kaninchen

Klonalität

  • 36
Polyklonal

Konjugat

  • 11
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Myc Target 1 Antikörper ist unkonjugiert

Applikation

  • 30
  • 13
  • 13
  • 11
  • 10
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.

    Aufreinigung

    MYCT1 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.

    Isotyp

    IgG
  • Applikationshinweise

    MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    MYCT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    Myc Target 1 (MYCT1)

    Andere Bezeichnung

    MYCT1

    Hintergrund

    MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.

    Molekulargewicht

    26 kDa

    Gen-ID

    80177

    NCBI Accession

    NP_079383

    UniProt

    Q8N699
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