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BCAR3 Antikörper (N-Term)

BCAR3 Reaktivität: Human, Maus, Ratte WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991737
  • Target Alle BCAR3 Antikörper anzeigen
    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
    Bindungsspezifität
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 30-80, N-Term
    Reaktivität
    • 11
    • 5
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 11
    • 2
    • 1
    Kaninchen
    Klonalität
    • 12
    • 2
    Polyklonal
    Konjugat
    • 14
    Dieser BCAR3 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Spezifität
    At least four isoforms of BCAR3 are known to exist, this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.
    Aufreinigung
    BCAR3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3. The immunogen is located within amino acids 30 - 80 of BCAR3.
    Isotyp
    IgG
    Top Product
    Discover our top product BCAR3 Primärantikörper
  • Applikationshinweise
    BCAR3 antibody can be used for detection of BCAR3 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    BCAR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    BCAR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
    Andere Bezeichnung
    BCAR3 (BCAR3 Produkte)
    Synonyme
    NSP2 antikoerper, SH2D3B antikoerper, AI131758 antikoerper, AND-34 antikoerper, BCAR3 antikoerper, breast cancer anti-estrogen resistance 3 antikoerper, breast cancer anti-estrogen resistance 3 L homeolog antikoerper, BCAR3 antikoerper, Bcar3 antikoerper, bcar3 antikoerper, bcar3.L antikoerper
    Hintergrund
    BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
    Molekulargewicht
    91 kDa
    Gen-ID
    8412
    NCBI Accession
    NP_003558
    UniProt
    O75815
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