Western Blotting (WB), ELISA, Immunofluorescence (IF)
Spezifität
Two alternatively spliced transcript variants have been observed.
Aufreinigung
ANG Antibody is affinity chromatography purified via peptide column.
Immunogen
ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG. The immunogen is located within amino acids 70 - 120 of ANG.
ANG antibody can be used for detection of ANG by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
ANG Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
ANG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ALS9 antikoerper, HEL168 antikoerper, RNASE4 antikoerper, RNASE5 antikoerper, ANG antikoerper, AI385586 antikoerper, Ang1 antikoerper, Rnase5 antikoerper, Rnase5a antikoerper, ANG1 antikoerper, angiogenin antikoerper, angiogenin, ribonuclease, RNase A family, 5 antikoerper, ribonuclease A family member k6 antikoerper, ANG antikoerper, Ang antikoerper, RNASE6 antikoerper
Hintergrund
ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.