ANG Antikörper (AA 70-120)

Produktnummer ABIN6991733

Der Kaninchen Polyklonal Anti-ANG-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, ANG in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ANG Antikörper (AA 70-120) (ABIN6991733)

Target: ANG (Angiogenin (ANG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-ANG Antikörper

Bindungsspezifität: AA 70-120

Spezifität: Two alternatively spliced transcript variants have been observed.

Aufreinigung: ANG Antibody is affinity chromatography purified via peptide column.

Immunogen: ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG. The immunogen is located within amino acids 70 - 120 of ANG.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ANG antibody can be used for detection of ANG by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ANG Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ANG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ANG

Target: ANG (Angiogenin (ANG))

Andere Bezeichnung: ANG

Hintergrund: ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.

Molekulargewicht: 16 kDa

Gen-ID: 283

NCBI Accession: NP_001136

UniProt: P03950