VAMP7 Antikörper (N-Term)

Produktnummer ABIN6991714

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VAMP7 in ELISA, WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für VAMP7 Antikörper (N-Term) (ABIN6991714)

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAMP7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-VAMP7 Antikörper

Bindungsspezifität: AA 20-70, N-Term

Spezifität: At least three isoforms of VAMP7 are known to exist, this antibody will detect the two longest isoforms. This antibody is predicted to not cross-react with other Ras-related proteins.

Aufreinigung: VAMP7 Antibody is affinity chromatography purified via peptide column.

Immunogen: VAMP7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human VAMP7. The immunogen is located within amino acids 20 - 70 of VAMP7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: VAMP7 antibody can be used for detection of VAMP7 by Western blot at 0.5 - 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: VAMP7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: VAMP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu VAMP7

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Andere Bezeichnung: VAMP7

Hintergrund: VAMP7 Antibody: VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.

Molekulargewicht: Predicted: 24, 29 kDa

Observed: 32 kDa

Gen-ID: 6845

NCBI Accession: NP_001172112

UniProt: P51809