RAB21 Antikörper (C-Term)

Produktnummer ABIN6991713

Dieses Anti-RAB21-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAB21 in WB, ELISA und IF. Geeignet für Human, Ratte und Maus.

Kurzübersicht für RAB21 Antikörper (C-Term) (ABIN6991713)

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-RAB21 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody is predicted to not cross-react with other Ras-related proteins

Aufreinigung: RAB21 Antibody is affinity chromatography purified via peptide column.

Immunogen: RAB21 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RAB21. The immunogen is located within the last 50 amino acids of RAB21.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RAB21 antibody can be used for detection of RAB21 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RAB21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RAB21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RAB21

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Andere Bezeichnung: RAB21

Hintergrund: RAB21 Antibody: RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the α,-tail of endocytosed integrin.

Gen-ID: 23011

NCBI Accession: NP_055814

UniProt: Q9UL25