YPEL3 Antikörper (N-Term)

Produktnummer ABIN6991665

Dieses Anti-YPEL3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von YPEL3 in ELISA, WB, IF und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für YPEL3 Antikörper (N-Term) (ABIN6991665)

Target: YPEL3 (Yippee-Like 3 (YPEL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YPEL3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-YPEL3 Antikörper

Bindungsspezifität: AA 20-70, N-Term

Aufreinigung: YPEL3 Antibody is affinity chromatography purified via peptide column.

Immunogen: YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3. The immunogen is located within amino acids 20 - 70 of YPEL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: YPEL3 antibody can be used for detection of YPEL3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: YPEL3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: YPEL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu YPEL3

Target: YPEL3 (Yippee-Like 3 (YPEL3))

Andere Bezeichnung: YPEL3

Hintergrund: YPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

Gen-ID: 83719

NCBI Accession: NP_113665

UniProt: P61236