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SIGLEC15 Antikörper (N-Term)

SIGLEC15 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991662
  • Target Alle SIGLEC15 Antikörper anzeigen
    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 2
    • 1
    AA 50-100, N-Term
    Reaktivität
    • 25
    • 10
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 23
    • 2
    Kaninchen
    Klonalität
    • 23
    • 2
    Polyklonal
    Konjugat
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIGLEC15 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 12
    • 10
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    SIGLEC15 antibody is predicted to not cross-react with other SIGLEC family members.
    Aufreinigung
    SIGLEC15 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    SIGLEC15 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SIGLEC15. The immunogen is located within amino acids 50 - 100 of SIGLEC15.
    Isotyp
    IgG
    Top Product
    Discover our top product SIGLEC15 Primärantikörper
  • Applikationshinweise
    SIGLEC15 antibody can be used for detection of SIGLEC15 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    SIGLEC15 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    SIGLEC15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
    Andere Bezeichnung
    SIGLEC15 (SIGLEC15 Produkte)
    Synonyme
    RGD1565948 antikoerper, CD33L3 antikoerper, HsT1361 antikoerper, SIGLEC-15 antikoerper, Cd33l3 antikoerper, EG620235 antikoerper, SIGLEC-I antikoerper, sialic acid binding Ig-like lectin 15 antikoerper, sialic acid binding Ig like lectin 15 antikoerper, Siglec15 antikoerper, SIGLEC15 antikoerper
    Hintergrund
    SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
    Molekulargewicht
    Predicted: 36 kDa

    Observed: 42 kDa
    Gen-ID
    284266
    NCBI Accession
    NP_998767
    UniProt
    Q6ZMC9
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