FOXRED2 Antikörper (N-Term)

Produktnummer ABIN6991660

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXRED2 in ELISA, WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FOXRED2 Antikörper (N-Term) (ABIN6991660)

Target: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXRED2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-FOXRED2 Antikörper

Bindungsspezifität: AA 70-120, N-Term

Aufreinigung: FOXRED2 Antibody is affinity chromatography purified via peptide column.

Immunogen: FOXRED2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FOXRED2. The immunogen is located within amino acids 70 - 120 of FOXRED2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FOXRED2 antibody can be used for detection of FOXRED2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: FOXRED2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: FOXRED2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu FOXRED2

Target: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Andere Bezeichnung: FOXRED2

Hintergrund: FOXRED2 Antibody: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

Gen-ID: 80020

UniProt: Q8IWF2

Pathways: SARS-CoV-2 Protein Interaktom