C9ORF116 Antikörper (N-Term)

Produktnummer ABIN6991649

Der Kaninchen Polyklonal anti-C9ORF116 Antikörper wird verwendet zum Nachweis von C9ORF116 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und ICC.

Kurzübersicht für C9ORF116 Antikörper (N-Term) (ABIN6991649)

Target: C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C9ORF116 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-C9ORF116 Antikörper

Bindungsspezifität: N-Term

Spezifität: PIERCE1 antibody is predicted to not cross-react with other UPF0691 family members.

Aufreinigung: PIERCE1 Antibody is affinity chromatography purified via peptide column.

Immunogen: PIERCE1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human PIERCE1. The immunogen is located within the first 50 amino acids of PIERCE1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PIERCE1 antibody can be used for detection of PIERCE1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PIERCE1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PIERCE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu C9ORF116

Target: C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))

Andere Bezeichnung: PIERCE1

Hintergrund: PIERCE1 Antibody: PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.

Gen-ID: 138162

UniProt: Q5BN46