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MLIP Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MLIP in WB, ELISA, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6991648

Kurzübersicht für MLIP Antikörper (C-Term) (ABIN6991648)

Target

MLIP (Muscular LMNA-Interacting Protein (MLIP))

Reaktivität

  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 5
Kaninchen

Klonalität

  • 5
Polyklonal

Konjugat

  • 5
Dieser MLIP Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Bindungsspezifität

    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    At least three isoforms of MLIP are known to exist.

    Aufreinigung

    MLIP Antibody is affinity chromatography purified via peptide column.

    Immunogen

    MLIP antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MLIP. The immunogen is located within the last 50 amino acids of MLIP.

    Isotyp

    IgG
  • Applikationshinweise

    MLIP antibody can be used for detection of MLIP by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    MLIP Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    MLIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    MLIP (Muscular LMNA-Interacting Protein (MLIP))

    Andere Bezeichnung

    MLIP

    Hintergrund

    MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies

    Gen-ID

    90523

    NCBI Accession

    NP_612636

    UniProt

    Q5VWP3
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