PPHLN1 Antikörper (AA 160-210)

Produktnummer ABIN6991643

Der Kaninchen Polyklonal Anti-PPHLN1-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, PPHLN1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PPHLN1 Antikörper (AA 160-210) (ABIN6991643)

Target: PPHLN1 (Periphilin 1 (PPHLN1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPHLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PPHLN1 Antikörper

Bindungsspezifität: AA 160-210

Aufreinigung: Periphilin Antibody is affinity chromatography purified via peptide column.

Immunogen: Periphilin antibody was raised against a 16 amino acid synthetic peptide near the center of human Periphilin. The immunogen is located within amino acids 160 - 210 of Periphilin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Periphilin antibody can be used for detection of Periphilin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Periphilin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Periphilin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PPHLN1

Target: PPHLN1 (Periphilin 1 (PPHLN1))

Andere Bezeichnung: Periphilin

Hintergrund: Periphilin Antibody: Periphilin, known as PPHLN1 or gastric cancer antigen Ga50, plays a role in epithelial differentiation and contributes to epidermal integrity and barrier formation. It interacts with periplakin, a known precursor of the cornified cell envelope. Periphilin 1 is ubiquitously expressed and localizes to nucleus and cytoplasm. Existing as eight alternatively spliced isoforms, Periphilin is highly insoluble and contains a putative nuclear localization signal (NLS) within its N-terminal half, a prerequisite for the formation of insoluble complexes and a possible caspase recognition sequence and a potential nuclear export signal. Periphilin may play an important role in the nervous system.

Gen-ID: 51535

NCBI Accession: NP_958848

UniProt: Q8NEY8