SIPA1 Antikörper (N-Term)

Produktnummer ABIN6991630

Produktdetails anti-SIPA1 Antikörper

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Bindungsspezifität: AA 40-90, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIPA1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Spezifität: At least three isoforms of SIPA1 are known to exist, this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.

Aufreinigung: SIPA1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1. The immunogen is located within amino acids 40 - 90 of SIPA1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SIPA1 antibody can be used for detection of EPAC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SIPA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SIPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Andere Bezeichnung: SIPA1 (SIPA1 Produkte)

Synonyme: Spa1 antikoerper, SPA1 antikoerper, signal-induced proliferation-associated 1 antikoerper, Signal peptidase I (leader peptidase I) antikoerper, signal-induced proliferation associated gene 1 antikoerper, SIPA1 antikoerper, sipA1 antikoerper, Sipa1 antikoerper

Hintergrund: SIPA1 Antibody: Signal-induced proliferation 1 (SIPA1) is a member of the SIPA1 family of RapGAPs, a family of mitogen-induced GTPase activating proteins. SIPA1 exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. When abnormally or prematurely expressed, SIPA1 may also hamper mitogen-induced cell cycle progression and may increase metastases in human cancers.

Gen-ID: 6494

UniProt: Q96FS4

Pathways: Response to Water Deprivation