Thymopoietin Antikörper (N-Term)
Kurzübersicht für Thymopoietin Antikörper (N-Term) (ABIN6991614)
Target
Alle Thymopoietin (TMPO) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 80-130, N-Term
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Spezifität
- At least three isoforms of Thymopoietin are known to exist, this antibody will detect all isoforms. Thymopoietin antibody is predicted to not cross-react with other LEM domain-containing proteins.
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Aufreinigung
- Thymopoietin Antibody is affinity chromatography purified via peptide column.
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Immunogen
- Thymopoietin antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Thymopoietin. The immunogen is located within amino acids 80 - 130 of Thymopoietin.
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Isotyp
- IgG
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Applikationshinweise
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Thymopoietin antibody can be used for detection of Thymopoietin by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Thymopoietin Antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- Thymopoietin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Thymopoietin (TMPO)
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Andere Bezeichnung
- Thymopoietin
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Hintergrund
- Thymopoietin Antibody: Thymopoietin (TMPO), also known as LAP2, is a widely expressed lem-domain-containing nuclear protein that is thought to play an important role in the regulation of nuclear architecture by binding lamin B1 and chromosomes in a manner regulated by phosphorylation during mitosis. Thymopoietin associates with nucleoplasmic lamins A/C, which are encoded by the dilated cardiomyopathy (DCM) gene LMNA, mutations in Thymopoietin disrupt this binding, suggesting that Thymopoietin may be a candidate disease gene for DCM.
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Gen-ID
- 7112
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NCBI Accession
- NP_003267
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UniProt
- P42166
Target
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