PRICKLE2 Antikörper (AA 420-470)

Produktnummer ABIN6991607

Der Kaninchen Polyklonal Anti-PRICKLE2-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, PRICKLE2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PRICKLE2 Antikörper (AA 420-470) (ABIN6991607)

Target: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRICKLE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-PRICKLE2 Antikörper

Bindungsspezifität: AA 420-470

Spezifität: Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members.

Aufreinigung: PRICKLE2 Antibody is affinity chromatography purified via peptide column.

Immunogen: PRICKLE2 antibody was raised against a 15 amino acid synthetic peptide near the center of human PRICKLE2. The immunogen is located within amino acids 420 - 470 of PRICKLE2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PRICKLE2 antibody can be used for detection of PRICKLE2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PRICKLE2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PRICKLE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PRICKLE2

Target: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Andere Bezeichnung: PRICKLE2

Hintergrund: PRICKLE2 Antibody: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.

Gen-ID: 166336

NCBI Accession: NP_942559

UniProt: Q7Z3G6