AFAP1L1 Antikörper (N-Term)

Produktnummer ABIN6991605

Dieses Anti-AFAP1L1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AFAP1L1 in WB, ELISA, IF und ICC. Geeignet für Human und Maus.

Kurzübersicht für AFAP1L1 Antikörper (N-Term) (ABIN6991605)

Target: AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFAP1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-AFAP1L1 Antikörper

Bindungsspezifität: AA 70-120, N-Term

Spezifität: At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members.

Aufreinigung: AFAP1L Antibody is affinity chromatography purified via peptide column.

Immunogen: AFAP1L1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human AFAP1L1. The immunogen is located within amino acids 70 - 120 of AFAP1L.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AFAP1L Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AFAP1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu AFAP1L1

Target: AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

Andere Bezeichnung: AFAP1L

Hintergrund: AFAP1L Antibody: The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation (1, 4). Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.

Gen-ID: 134265

NCBI Accession: NP_689619

UniProt: Q8TED9