SEC62 Antikörper (C-Term)

Produktnummer ABIN6991578

Produktdetails anti-SEC62 Antikörper

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Bindungsspezifität: AA 270-320, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC62 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.

Aufreinigung: SEC62 Antibody is affinity chromatography purified via peptide column.

Immunogen: SEC62 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SEC62. The immunogen is located within amino acids 270 - 320 of SEC62.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SEC62 antibody can be used for detection of SEC62 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SEC62 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SEC62 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Andere Bezeichnung: SEC62 (TLOC1 Produkte)

Synonyme: tloc1 antikoerper, TLOC1 antikoerper, wu:fb57b06 antikoerper, zgc:114073 antikoerper, Dtrp1 antikoerper, HTP1 antikoerper, TP-1 antikoerper, 3100002M17Rik antikoerper, AI844545 antikoerper, AW545092 antikoerper, Tloc1 antikoerper, Ab2-292 antikoerper, SEC62 homolog, preprotein translocation factor S homeolog antikoerper, SEC62 homolog, preprotein translocation factor antikoerper, membrane unit of ER protein translocation apparatus antikoerper, SEC62 homolog (S. cerevisiae) antikoerper, sec62.S antikoerper, SEC62 antikoerper, sec62 antikoerper, Sec62 antikoerper

Hintergrund: SEC62 Antibody: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.

Gen-ID: 7095

NCBI Accession: NP_003253

UniProt: Q99442